Nowadays, mainstream oncology research focuses more on different toxic treatments that could hamper people’s health. Due to the high rate of people suffering from tumors, whether benign or malignant, more and more drug establishments and medical companies are earning big time but remain vilely negligent to the protection of public health. Among the most notable, yet underestimated natural agents is curcumin derived from turmeric. Turmeric for tumors is a potent natural plant that has several promising benefits to suppress tumors including antiangiogenic, anti-proliferative and anti-tumorigenic activities. To better understand how curcumin treats tumors, it is recommended to learn how it grows and how curcumin disrupts further growth and proliferation.
Tumors usually form when there is a disregulation of the cell cycle. This disregulation often occurs when there are problems with the immune system due to excessive drinking, viruses, obesity, chemical and radiation exposure, excessive sunlight and genetics. Although tumors may be malignant or cancerous, most tend to be benign. Tumor angiogenesis is one of the major mechanisms leading to tumor growth and progression. Since tumors need new blood vessels for nourishment, they are endowed with the ability to spontaneously sprout new blood vessels just like any normal tissue. Angiogenesis in abnormal tissue or tumor is their primary means of growth.
Taking turmeric for tumors can be favorable for people looking for natural and inexpensive tumor treatments. Its active ingredient curcumin contains several active constituents that contribute to anti-tumor, chemopreventive and anti-inflammatory body power. By inhibiting the inflammatory master element Nuclear Factor-Kappa B (NF-kB), curcumin curbs cancer-causing inflammation, cutting the levels of cytokines all over the body. Curcumin may also interfere with the development of advanced glycation end products that can lead to cellular mutation.
Curcumin is known to inhibit carcinogenesis and the common link for this mechanism is its antiangiogenic effect. It is a primary inhibitor of angiogenesis as it downregulates proangiogenic proteins such as basic fibroblast growth factors and vascular endothelial growth factors. In addition, it has an inhibitory activity on signal transduction pathways including protein kinase C and NF-Kb. Curcumin’s potent antiangiogenic effect can interfere with the production of these proteins as well as prevent tumor cells from making a feasible blood supply.
Besides being an antiangiogenic, curcumin’s anti-tumor and anti-proliferative activities makes it cytotoxic to a wide array of tumor cells, regardless of its tissue origin. The major mechanism for its cytotoxicity is its ability to induce apoptosis (cell death). Since it inhibits the production of NF-kB, curcumin thereby prevents its entry into the cell nucleus, reducing the expression of cell-cycle regulatory proteins and other survival factors. With this mechanism, it is safe to say that curcumin also acts as an antimetastatic agent against various cancer types.
Indeed, with the high curcumin levels found in turmeric, the use of turmeric for tumors has become increasingly popular. Curcumin, its pharmacologic component, has emerged as a valuable tumor and cancer-preventing treatment, with multi-modal effects acting simultaneously to suppress and shrink tumors, be they benign or cancerous. Truly, this ultimate Ayurvedic herb offers promising health benefits in countering tumors and cancer.